I knew Amy since 1988, when she was a post-doc in the lab Hiroshi Nikaido. She came to visit Maurice Hofnung lab, along with Hiroshi and David Dean. I was working on MalF and MalG, the membrane proteins of the maltose transport system of E. coli. They came to show us their latest findings in the context of a private seminar. Amy was on the way to reconstitute the maltose transport system in proteoliposomes, from purified components, thereby demonstrating conclusively that ATP only was responsible for energizing the system. I still remember this seminar, I was struck by the rigor she showed in her so delicate reconstitution experiments, by the attention she wore to the purity criteria of her protein and lipid preparations, and also by the intelligence and sweetness that emanated from her eyes.
We had the opportunity to meet several times since, at the Gordon Conferences on Bacterial Cell Surfaces, every two years between 1990 and 2002, and for some odd years in Gosaü, at the ABC meetings between 1997 and 2001. This is also in one of the latter conferences that the idea emerged to write a review on ABC systems. It took time since 2001 to make it happen. I kept a few drafts, dating from 2001 to 2006. We met one last time in Paris, but I do not remember the date exactly. Amy came from a conference she had given in Germany, en route for the US, and she spent two days in Paris at the Pasteur Institute, to give a seminar and to talk with me. We then agreed on the division of labor. For Amy, the overall coordination of the review, import and export, Jue Chen for the structure and mechanism, for Cedric Orelle, the efflux mechanisms and the resistance to drugs, and for me, the general introduction, the description of ABC families and the hypothesis in the evolution of ABC proteins. This beautiful project was finally realized in 2008, and all the feedback I received indicated that the scientific community awaited this review, which has been recognized as a significant contribution to the knowledge of ABC systems. The establishment of the structure of the maltose transporter, by Jue and Amy the previous year, also contributed to the success of this review.
I keep of Amy the image of a nice person, almost shy, modest and discreet, but with an uncommon intelligence, a remarkable ability to work very hard and with high quality, a superior organization, and boldness in conceiving and realizing experiments. The maltose community, and that of ABC systems, will be indebted to her for many years.
Amy, I will miss you.
I met Amy several times as a fellow microbiologist and a colleague in the ABC field. A wonderful human being, kind, sincere and great to talk to. She made a huge contribution to science and I cannot believe that she has gone but she leaves behind warm memories and a lasting legacy of great science. My sympathies to the family and all her close colleagues - we shall not forget Amy.
Amy was a wonderful scientist, and a very nice person. She has been a great source of inspiration for scientists from all over the world who work on ABC transporters. We will miss her a lot.
I learned a lot from your way of doing science, I will miss you.
My condolences to your family.
Amy will be greatly missed -- she was a fantastic advisor and wonderful person. I am so fortunate to have known her and I learned so much with her guidance. My deepest sympathies to Fred and Nathan.