SMITH--Charles G., Ph.D., An internationally prominent biochemist and pharmaceutical industry executive, died on May 1, 2013, in Carlsbad, CA. He was 85. Beginning in the 1950's, Dr. Smith carried out personal research in the fields of antibiotics, cancer and industrial molecular biology. As a pharmaceutical executive, he had direct administrative responsibility for total drug discovery and development programs in many fields, including infectious diseases, cancer and cardiovascular diseases over a 30 year period. Dr. Smith was directly involved in or administratively responsible for the discovery, licensing and marketing of approximately 20 major medications and products. Dr. Smith was a co-founder and Director of Vanguard Medica, Ltd., Guildford, UK, and served on the Boards of Directors of Chemex Pharmaceuticals (Fort Lee, NJ) and Dura Pharmaceuticals (San Diego, CA). Charles Giles Smith was born on October 27, 1927, in Chicago, Il. He received a Bachelor of Science degree in chemistry from the Illinois Institute of Technology in 1950, a Master of Science degree in biochemistry from Purdue University
in 1952, and a Ph.D. in biochemistry from the University of Wisconsin in 1954. He served in the United States Army from 1946 to 1947, from which he was honorably discharged. Dr. Smith began his professional career at The Upjohn Company, Kalamazoo, Michigan, where he worked from 1954 to 1967. Between 1967 and 1975, he was the Vice President, Research and Development and President, Squibb Institute for Medical Research (1974) at E.R. Squibb & Sons, Princeton, NJ. He was the Vice President, Research and Development of the Revlon Health Care Group, Tuckahoe, NY, from 1975 to 1986. After retiring in 1986, Dr. Smith served as a pharmaceutical consultant on a worldwide basis. He was an Adjunct Professor at San Diego State University for several years. He authored 50 full papers, abstracts and notes in major scientific publications and the book "The Process of New Drug Discovery and Development," CRC Press, Boca Raton, FL, 1992. Dr. Smith lectured extensively on various aspects of pharmaceutical research and development during the course of his career. In addition to his passion for scientific discovery, Dr. Smith enjoyed Italian opera, food and culture, military history, and lively discourse with children and adults alike. He engaged all people he encountered. He was a humanitarian and a true gentleman. Dr. Smith was a devoted husband, father and grandfather. He is survived by his beloved wife of 63 years, Angeline F. Smith, sons Giles, Kevin and Jeffrey Paul, daughter Tracy, ten grandchildren and one great-grandchild.