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JAMES TILL Obituary

August 25, 1931 - May 18, 2025 Dr. James Edgar Till O.C., O.Ont., Ph.D., F.R.S., F.R.S.C. Passed away peacefully on May 18, 2025, in his 94th year, in the Palliative Care Unit, Michael Garron Hospital, Toronto. He is remembered with love by his wife of over 65 years, Joyce; his children, David (Barbara), Karen (David), and Susan; his grandchildren, Meghan, Stefan, Brian, Daniel, Nikolas, and Jimmy; his great-grandchild, Finley; his nephew and nieces, Bruce, Barb, and Margo, and their families. He was predeceased by his brother, Bill, his sister-in-law, Gene, and his nephew, Rob. Jim was born and raised on a farm in Lloydminster, Alberta, of which he had fond memories. Choosing a career in science, he received scholarships for the University of Saskatchewan (B.Sc., 1952; M.Sc., 1954) and a Ph.D. from Yale University (1957). He was recruited to the Ontario Cancer Institute at Princess Margaret Hospital, where he worked with Dr. Ernest McCulloch, who became a long-time collaborator and friend. Together, they demonstrated the existence of stem cells, which had a significant impact on medical research, though Jim, always humble, downplayed his role. In the 1980s, Jim's fields of interest expanded to bioethics and the potential of the Internet in medical research. He held a number of leadership and teaching roles and received numerous honours, including the Gairdner Foundation International Award (with Dr. McCulloch in 1969), Officer of the Order of Canada (1994), and Fellow of the Royal Society (2000). He remained active in research up to the end of his life. Through all of this, his children rarely heard from him about his work as a scientist but simply knew him as Dad. Among the virtues he passed on to his children were the value of perseverance, the importance of treating everyone with respect, a love of humour, and a sense of curiosity: "Let's look it up!" was a commonly heard phrase as he reached for an encyclopedia from the bookshelf, or in his later years, searched on his phone. His family has memories of going on summer camping trips, with Jim stopping the car whenever he spotted a historical plaque. He would take his kids to the C.N.E. each summer (only once losing a child), go on training outings with them to prepare for the Miles for Millions charity walk, and lead games with them in the backyard pool. His arch nemeses were the backyard squirrels who foiled every one of Jim's elaborate designs intended to keep them out of the bird feeder. He was a lifelong curler, only stopping at 88 when COVID made curling difficult. Jim was always supported, with grace, strength, and humour, by his wife, Joyce. Their love for each other was evident in the playful banter they shared. Jim's goal in his later years was to stay with her in their condo as long as he could, watching curling and tennis together in between family visits. Thanks to her, he was able to do this until the last month of his life. The family appreciates the care he then received at Michael Garron Hospital. A private family gathering will be held to celebrate Jim's life. In his memory, donations may be made to the Princess Margaret Cancer Foundation.

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Published by The Globe and Mail from May 22 to May 26, 2025.

Memories and Condolences
for JAMES TILL

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10 Entries

Tak W Mak

June 15, 2025

Obituary Note on James Till´s Passing June 2025

To Joyce and the entire Till family, please accept my deepest condolences on the occasion of James´ passing. I will always consider it a great privilege to have been part of the academic family of Till and McCulloch, and to have benefitted from the magnitude of their ground-breaking discovery of hematopoietic stem cells (HSCs). This amazing team´s contributions to science, particularly to elucidating the process of hematopoiesis, are unparalleled and recognized internationally as establishing the very foundations of the field.

The mentorship I received from the Till and McCulloch partnership was of the most useful kind, both personally and professionally. I learned about the rigour needed to produce the best science from Till, and how to balance it with the sometimes more adventurous approach of McCulloch. I observed how, although Till was always totally committed to his science, he was never overbearing or unkind in his criticisms of a trainee´s work, and did his best to steer them to a path of better experimentation. He was the epitome of scientific reserve and cautious hypothesizing, and often had to rein in the more theatrical thrusts of McCulloch. I owe both of these brilliant men a great deal, not the least of which was the opportunity to independently pursue seemingly odd questions in the lab.

James Till, a giant of Canadian biomedical science, will long be remembered as a pioneer whose work set the stage for not only the treatment of many blood cancers but also the development of the exciting arena of regenerative medicine. I will long remember him as a humble but exemplary leader, looked up to by many still active in the field today. He will be sorely missed.

Marg Schneider (nee Whitmore)

June 15, 2025

I met Jim in 1953 when he and my brother, Gordon Whitmore, were graduate students under Dr. Harold Johns. Their master's project was the design of the world's first Cobalt 60 radiotherapy unit at the University of Saskatchewan.
Jim was studious and inquisitive & had a very pleasant personality. He also had a great sense of fun which led to many humorous pranks carried out with his colleagues.
Knowing Jim then, it doesn't surprise me that he went on to make many significant contributions to the scientific world, especially the discovery of stem cells.
My sympathies go out to Joyce and the family and I hope that pleasant memories of a life well lived help to sustain them through this sad time.
Marg Schneider (nee Whitmore)

Ruth Abernethy

June 5, 2025

My heartfelt condolences to the Till family. In sculpting portraits of J. Till and E. McCulloch (Toronto and Vancouver) I became familiar with the details of Jim's remarkable life, but I don't often meet the characters I portray. My brief time with Mr. Till was an honour. I most admired his inherent capacity to summon the best from everyone around him, with insight and humour.

Elizabeth Greisman

June 5, 2025

Dear Till family and Joyce,
I am so sorry to hear of the passing of Dr. Till. I send my deepest condolences to you. He was an exceptional man. Perhaps you remember that I painted several portraits of Dr. Till for an exhibition honouring the discovery of the stem cell. I completed the preparatory sketches in your home. I have photos of a large portrait, and of a small portrait , which I would be happy to share. There is a large painting of Dr. Till and and Dr. Mc Cullough , I would be happy to photograph and share with you. Dr. Till was a great inspiration to us all.
I am thinking of you at this very sad time. I am very thankful that I met Dr. Till and Joyce.

Gwen Johns Greenstock

May 29, 2025

I have known Jim for about 75 years, since I was five or six years old, when he first came to the University of Saskatchewan and was a student of my father, Dr. Harold Johns. I was last in touch with Jim early in 2025 and he did not mention he was ill, so I was shocked to read of his passing. Jim was an amazing scientist and a very nice man. And his passing was really the end of an era as all of his scientific contemporaries, former students of my father, passed before him. My sisters, Claire and Marilyn and I can never hear the song "The Great Pretender" without thinking of Jim belting it out around a campfire at our family cottages in Prince Albert National Park in SK and in Haliburton, ON. May he rest in peace and may his memory be a blessing to Joyce and his children and extended family and to all his friends who knew and loved him.

Bob Phillips

May 28, 2025

I learned of Jim´s novel stem cell work when I was a graduate student in St. Louis and wrote to him to see if he had postdoctoral positions available. He offered a position in his lab so in November 1965, my family moved to Toronto. When, after two years, I was offered a staff position, I immediately accepted. During my many years subsequently, Jim was always willing to provide advice and support. His passion for research excellence and his great breadth of knowledge often lead to unique proposals for moving forward. I will always cherish the memories of our many interactions. My condolences to the family.

Mary Gospodarowicz

May 24, 2025

I met Jim Till at the Princess Margaret Hospital first as trainee / resident and then as a colleague. In addition to being a brilliant scientist, Jim was known for instilling a culture of inquiry and constant quest for new knowledge. I remember well when he moved from the top research floors down to the clinic to investigate medical decision making and health-related quality of life assessment with the same scientific rigor and enthusiasm as he had for basic research. Always curious, always pushing us to do more. Life well lived. Condolences to the family.

Suzanne Dunford

May 23, 2025

Sending condolences from the Marguerite Hunt and family. Jim was a member of our Princess Margaret Hospital family and we were blessed to know him. Marguerite (my mother) always spoke of both Joyce and Jim with great fondness. Hugs from the Hunts and especially Marguerite.

Ronald Worton

May 22, 2025

As a student of Jim's from 1965-69, I learned more from him than from anyone else in my lifetime. He taught me to focus only on problems of importance, to use scientific rigor in the approach to problem solving, to demand integrity in generating and reporting results, and to be humble when asked to speak about the work. Joyce, David, Karen and Susan, your husband and father was a role model for scientists all over the world. He will be missed.

Alan Bernstein

May 22, 2025

I was a grad student in Jim Till's lab between 1968-1972. Jim taught me many things, mostly about life, how one should deal with the many bumps and trials along life's journey, and how to curl (I think I flunked that one). One story among many: Jim of course was famous for his discovery with Bun McCulloch, of stem cells in the blood forming system. One day when I was in the lab he announced he was leaving the field and was going to study how women with breast cancer were forming support groups virtually on this new thing called the web. When I asked him why he was leaving the stem cell field, his answer was typical Jim: "Because I don't want to compete with my former graduate students!!!" All said in his emphatic way. With his passing, the world has lost a great scientist and Canada has lost a great Canadian. Joyce, please accept my sincerest condolences on Jim's passing.

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