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Yale University

DAVID ORLOFF Obituary

Dr. DAVID ORLOFF
Died peacefully September 13, 2015 of brain cancer. He graduated from St. Albans School '75, Harvard '79 and New York University Medical School '84. He completed his medical training at Yale University and fellowship at the National Institutes of Health. His laboratory work in immunology at the NIH was published in Nature. As Director of the Division of Metabolism and Endocrinology Products at the FDA, he oversaw the approval of a new class of statin drugs. After achieving the rank of Captain in the Public Health Service in 2005, he joined Medpace Inc., where he was regarded as an industry opinion leader in the study of metabolic diseases and drug development. David is survived by his mother Dr. Martha Vaughan, sons Nicholas and Jeremy, former wife Dr. Catherine Orentreich, and his siblings, Jonathan, Gregory and Lee. A memorial service will be held at 2:30 p.m. on October 3, 2015 at the Cosmos Club in Washington DC.

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Published by The Washington Post on Sep. 21, 2015.

Memories and Condolences
for DAVID ORLOFF

Sponsored by David B. Karpf, MD.

16 Entries

David Brian Karpf

September 11, 2023

The world lost a great clinical endocrinologist and human being when David passed away.

Diann Kim

March 4, 2018

David: Thinking about you today. Diann

M David Wiener

February 1, 2017

I am a classmate and former close friend of David's from NYU Med School. We lost touch after school, though I remember being inivited and unable to attend his wedding. I recently uncovered an old photo album with pictures of us together in happy times which inspired me to atttempt to locate and contact him via the internet, only to discover this devastating news. My deepest delayed condolences to his family, he was one of the good guys. It is not fair.

January 7, 2016

Hi Guys, Annita (Seckinger) here. I only now heard the news. At the moment i am without word and the sadness is sooo deep that i feel like i have been hit with stun-gun. Unfortunately i have no words except that he will be missed something awful and not just by me. I just wanted to say my thoughts are with all of you right now. I know there is not much one can say at a time like this, so i will not even try. Much love.

Annita

David Karpf

December 31, 2015

I was floored to hear of David's premature passing. I respected and admired David, both as an excellent endocrinologist who was fair-minded when he headed CDER Endocrine & Metabolic, and for his drug development expertise when he was at MedPace (during which time I had the pleasure of working with him as both a member of my company's Clinical & Scientific Advisory Board, and as a key member of the MedPace team partnered with us in running our Phase 2b trial world-wide). The world has lost a true mensch. My heart goes out to his family and close friends.

RIP, David

Donna Ryan

October 12, 2015

As a clinician scientist in obesity research, I had the opportunity to work with Dr. Orloff during his time at the FDA and after. The field shall miss this fair-minded man and his many skills in evaluating medications for chronic weight loss. Please accept my deepest sympathy.

Roman Dvorak

October 12, 2015

So sorry to hear, I had a lot of respect for David as a person and a professional, he was bright and fun and always fun to talk to on any topic.

Lili Carr

September 29, 2015

Dear David's family,
No one can truly know what you are experiencing in this time of loss. Please accept my condolences and know that you are in my thoughts.

Jay Elliott

September 23, 2015

DGO was a great man and the embodiment of a physician scientist.

September 21, 2015

Sending my condolences to the family. May God give you strength and peace during this difficult time. (Psalm 29:11)

Janester Isaac

September 20, 2015

My thoughts and prayers are with the family of Dr. Orloff, I had the chance to briefly work with Dr. Orloff and during that time, he was the most caring and kind person to be around. Its very sad to hear, he will be greatly missed.

Erin Scully

September 18, 2015

To David's Family and Friends,
My thoughts and prayers are with your family. I am honored to have had the opportunity to work with him and learn from him. He will be greatly missed but always remembered.
-Erin Scully

Jennifer Carbon

September 17, 2015

I had profound respect for DGO (as we affectionately called him) as a colleague, but more importantly, as a person. He treated everyone with such warmth and sincerity. And his humor...that's one of the first things people mention. My thoughts and prayers to his family. A truly great man.

Karen Woodwell

September 17, 2015

My thoughts n prayers are with you! I worked with DGO for 8 years at Medpace. I did a lot of IT Support for David over the years. I enjoyed him imminently. Always a happy guy. My heart goes out for all of you.

Anne Marie Glover

September 17, 2015

Dear David's family,
Please know that you all are in my thoughts and prayers. I was privileged to indirectly work with DGO at Medpace, mostly by creating numerous slide sets for his many presentations and seeing him when he came into town since his office was near my cube. He always thanked me via email for the slides and always asked about my life and how home schooling my daughter was going. He also was a trusted voice and comfort when my parents were ill. I shall never forget his friendliness, kindness, and smiling face.
Sending my love and comfort,
Anne-Marie Glover

Regina Smith

September 17, 2015

Jeremy, my condolences to you and your family.

Showing 1 - 16 of 16 results